Brief Information of the Compound and Protein
Compound Name
2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-((S)-2-methylpyrrolidin-1-yl)ethyl)imidazolidin-2-ylidene)malononitrile
    Show/Hide
PubChem ID
CID: 44447987
Canonical SMILES
C[C@H]1CCCN1CCN1CCN(CCN2CCC[C@H]2C)C1=C(C#N)C#N
    Show/Hide
Compound Formula C20H32N6
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
Ki = 0.47 nM
   TI
   LI
   LO
   TS