Brief Information of the Compound and Protein
Compound Name
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
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PubChem ID
CID: 1548943
SID: 14923155
Canonical SMILES
COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
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Compound Formula C18H27NO3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 44.8 nM
   TI
   LI
   LO
   TS
2
Ki = 1700 nM
   TI
   LI
   LO
   TS
CL001009 CHO/VR1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 1808 nM
   TI
   LI
   LO
   TS
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
EC50 = 2320 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19 nM
2 Ki = 1800 nM