Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-3-hydroxy-4-{[(3-methoxyphenyl)methyl]amino}-1-phenylbutan-2-yl]benzamide
    Show/Hide
 PubChem ID
CID: 25190494
Canonical SMILES
CCNc1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(OC)c1)N1CCCCS1(=O)=O
    Show/Hide
Compound Formula C31H40N4O5S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 2
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
Q9Y5Z0
Gene Name
BACE2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4270 nM
   TI
   LI
   LO
   TS