Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6S,7S)-5-methanesulfonyl-6-(4-phenyl-piperazine-1-carbonyl)-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide
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 PubChem ID
CID: 44446842
Canonical SMILES
CS(=O)(=O)N1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO
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Compound Formula C20H28N4O5S
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 10
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
O14672
Gene Name
ADAM10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000218 BT-474
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 27 nM