Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6S,7S)-6-(4-m-tolyl-piperidine-1-carbonyl)-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide
    Show/Hide
 PubChem ID
CID: 44446807
Canonical SMILES
Cc1cccc(c1)C1CCN(CC1)C(=O)[C@H]1NCC2(CC2)C[C@@H]1C(=O)NO
    Show/Hide
Compound Formula C21H29N3O3
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 10
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
O14672
Gene Name
ADAM10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000218 BT-474
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 689 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 194 nM