Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ELAGOLIX SODIUM
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 PubChem ID
CID: 24785956
SID: 49710387
Canonical SMILES
COc1cccc(-c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](NCCCC(=O)[O-])c3ccccc3)c2=O)c1F.[Na+]
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Compound Formula C32H29F5N3NaO5
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Kd = 1.19 nM
   TI
   LI
   LO
   TS
2
Kd = 3.21 nM
   TI
   LI
   LO
   TS
3
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CL000194 RBL-1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS