Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(15R)-7-(trifluoromethyl)-17-oxa-4,11-diazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3(8),6,9-tetraen-5-one
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 PubChem ID
CID: 9839661
SID: 14800912
Canonical SMILES
FC(F)(F)c1cc(=O)[nH]c2cc3OC[C@H]4CCCN4c3cc12
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Compound Formula C15H13F3N2O2
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 26 nM
   TI
   LI
   LO
   TS
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 27 nM
   TI
   LI
   LO
   TS