Brief Information of the Compound and Protein
Compound Name
4-(6-(azetidin-1-yl)pyrimidin-4-ylamino)-N-(3-(4-fluoro-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-5-yl)benzamide
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PubChem ID
CID: 11720469
SID: 16825512
Canonical SMILES
Fc1ccc(cc1C(F)(F)F)-c1nsc(NC(=O)c2ccc(Nc3cc(ncn3)N3CCC3)cc2)n1
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Compound Formula C23H17F4N7OS
Compound Structure
Protein Name
Thrombopoietin receptor
Protein Classification
Membrane receptor
Uniprot ID
P40238
Gene Name
MPL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
EC50 = 81 nM
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