Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R,5R,6R)-2-Amino-3-benzhydryloxy-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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PubChem ID
CID: 11257636
SID: 16343084
Canonical SMILES
N[C@@]1([C@H]2[C@@H](C[C@H]1OC(c1ccccc1)c1ccccc1)[C@]2(F)C(O)=O)C(O)=O
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Compound Formula C21H20FNO5
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31421
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
2
IC50 = 24.4 nM
   TI
   LI
   LO
   TS
3
Ki = 2.58 nM
   TI
   LI
   LO
   TS