Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-(2,6-dichloro-phenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-6-yl]-ethanone
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 PubChem ID
CID: 15392101
Canonical SMILES
COc1ccc(cc1)C1N2C=C(SC2=NC(C)=C1C(=O)OCCN(C)C)c1c(Cl)cccc1Cl
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Compound Formula C25H25Cl2N3O3S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31421
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
2
Ki = 7000 nM
   TI
   LI
   LO
   TS