Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-4-(3-chlorophenyl)-8-(2-phenylethynyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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 PubChem ID
CID: 9864190
SID: 14828828
Canonical SMILES
Clc1cccc(c1)C1=Nc2ccc(cc2NC(=O)C1)C#Cc1ccccc1
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Compound Formula C23H15ClN2O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31421
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 80 nM
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