Brief Information of the Compound and Protein
Compound Name
(E)-4-(3-chlorophenyl)-8-methyl-1H-benzo[b][1,4]diazepin-2(3H)-one
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PubChem ID
CID: 44434256
Canonical SMILES
Cc1ccc2N=C(CC(=O)Nc2c1)c1cccc(Cl)c1
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Compound Formula C16H13ClN2O
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31421
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2820 nM
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