Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-(4-oxo-7-(2-phenylethynyl)-8-thiomorpholino-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)benzonitrile
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 PubChem ID
CID: 22448643
Canonical SMILES
O=C1CC(=Nc2cc(N3CCSCC3)c(cc2N1)C#Cc1ccccc1)c1cccc(c1)C#N
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Compound Formula C28H22N4OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31421
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 40 nM
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