Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-quinolin-4-yl]-piperazine-1-carbothioic acid (6-phenyl-pyridin-3-ylmethyl)-amide
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 PubChem ID
CID: 44394634
Canonical SMILES
COc1cc2c(N3CCN(CC3)C(=S)NCc3ccc(nc3)-c3ccccc3)c(cnc2cc1OCCCN1CCCCC1)C#N
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Compound Formula C36H41N7O2S
Compound Structure
Protein Name
 Protein Info 
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000197 MG-63
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
   TI
   LI
   LO
   TS