Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide
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 PubChem ID
CID: 2662
SID: 14755918
Canonical SMILES
Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
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Compound Formula C17H14F3N3O2S
Compound Structure
Protein Name
 Protein Info 
Prostaglandin G/H synthase 2
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
Q05769
Gene Name
PTGS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000158 J774
 Cell Line Info 
Mus musculus (Mouse)  5
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
2
IC50 = 61 nM
   TI
   LI
   LO
   TS
3
IC50 = 79 nM
   TI
   LI
   LO
   TS
4
IC50 = 80000 nM
   TI
   LI
   LO
   TS
5
IC50 = 95000 nM
   TI
   LI
   LO
   TS
CL000014 RAW 264.7
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 8.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.51 nM
2 IC50 = 9.3 nM
3 IC50 = 26.220567 nM
4 IC50 = 30 nM
5 IC50 = 39.81 nM
6 IC50 = 52.441135 nM
7 IC50 > 25000 nM