Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
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 PubChem ID
CID: 11560224
SID: 24736302
Canonical SMILES
FC(F)(F)CN(CC(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F
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Compound Formula C14H9F9N2O
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 0.2 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
3
Ki = 1.5 nM
   TI
   LI
   LO
   TS
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 1.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.2 nM
2 Ki = 1 nM
3 Ki = 1.5 nM
4 Ki = 4.6 nM