Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-cis retinoic acid
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 PubChem ID
CID: 449171
SID: 14898408
Canonical SMILES
C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
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Compound Formula C20H28O2
Compound Structure
Protein Name
 Protein Info 
Retinoic acid receptor RXR-alpha
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 2
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Nuclear hormone receptor subfamily 2 group B
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Nuclear hormone receptor subfamily 2 group B member 1
Uniprot ID
P19793
Gene Name
RXRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  4
1
AC50 = 7 nM
   TI
   LI
   LO
   TS
2
EC50 = 100 nM
   TI
   LI
   LO
   TS
3
EC50 = 195 nM
   TI
   LI
   LO
   TS
4
EC50 = 250 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 120 nM
   TI
   LI
   LO
   TS
3
EC50 = 170 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 4 nM
2 EC50 = 6 nM
3 EC50 = 13 nM
4 EC50 = 26 nM
5 EC50 = 100 nM
6 IC50 = 32 nM
7 Kd = 1.5 nM
8 Kd = 3 nM
9 Kd = 8 nM
10 Kd = 9 nM
11 Kd = 13 nM
12 Kd = 14 nM
13 Kd = 16 nM
14 Kd = 50 nM
15 Kd = 240 nM
16 Kd = 1560 nM
17 Kd = 1810 nM
18 Ki = 8 nM
19 Ki = 8.4 nM
20 Ki = 478 nM
21 Ki = 583 nM