Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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 PubChem ID
CID: 9828962
SID: 14788165
Canonical SMILES
COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1
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Compound Formula C30H40N6O4
Compound Structure
Protein Name
 Protein Info 
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CL000197 MG-63
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
2
IC50 = 1250 nM
   TI
   LI
   LO
   TS