Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

15-28-Somatostatin-28

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PubChem ID

CID: 16129706

SID: 14817579

Canonical SMILES	C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show/Hide
Compound Formula	C76H104N18O19S2

Compound Structure

Protein Name

Protein Info

Somatostatin receptor type 2

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Peptide receptor (family A GPCR)

Short peptide receptor (family A GPCR)

Somatostatin receptor

Uniprot ID

P30874

Gene Name

SSTR2

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000443	CC531 Cell Line Info	Rattus norvegicus (Rat)	1
1	IC50 = 0.4 nM	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	Ki = 0.049 nM	TI LI LO TS
2	Ki = 0.1995 nM	TI LI LO TS
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	EC50 = 0.1 nM	TI LI LO TS
2	Ki = 0.035 nM	TI LI LO TS
CL000351	Dede Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	IC50 = 0.67 nM	TI LI LO TS
2	IC50 = 0.7 nM	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 0.2 nM	TI LI LO TS

Biochemical Assays