Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid
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 PubChem ID
CID: 170364
SID: 12015156
Canonical SMILES
Cc1oc(nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1)-c1ccccc1
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Compound Formula C34H30N2O5
Compound Structure
Protein Name
 Protein Info 
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 1.4 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
EC50 = 0.3388 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.34 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.3388 nM
2 EC50 = 5 nM
3 IC50 = 25 nM
4 IC50 = 217 nM
5 Ki = 1.1 nM
6 Ki = 1.148 nM