Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
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 PubChem ID
CID: 4630
SID: 15121093
Canonical SMILES
O=C1CCCN1CC#CCN1CCCC1
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Compound Formula C12H18N2O
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
2
Ki = 17 nM
   TI
   LI
   LO
   TS
3
Ki = 323.59 nM
   TI
   LI
   LO
   TS
4
Ki = 660 nM
   TI
   LI
   LO
   TS
CL000845 CHO-K9
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
Ki = 147.91 nM
   TI
   LI
   LO
   TS
2
Ki = 851.14 nM
   TI
   LI
   LO
   TS
3
Ki = 1023.29 nM
   TI
   LI
   LO
   TS
4
Ki = 1778.28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 19 nM
2 Ki = 10000 nM