Brief Information of the Compound and Protein
Compound Name
9-chloro-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methyl-7-(trifluoromethyl)pyrido[1,2-a]pyrimidin-4-one
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PubChem ID
CID: 44376927
Canonical SMILES
Cc1nc2c(Cl)cc(cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1)C(F)(F)F
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Compound Formula C23H19ClF3N3O2
Compound Structure
Protein Name
Alpha-2A adrenergic receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Adrenergic receptor
Uniprot ID
P08913
Gene Name
ADRA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.175 nM
   TI
   LI
   LO
   TS