Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-ethyl-4-(trifluoromethyl)-1H,2H,6H,7H,8H,9H-pyrido[3,2-g]quinolin-2-one
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 PubChem ID
CID: 9839132
SID: 14800274
Canonical SMILES
CCC1CCNc2cc3[nH]c(=O)cc(c3cc12)C(F)(F)F
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Compound Formula C15H15F3N2O
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  4
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
2
EC50 = 4.1 nM
   TI
   LI
   LO
   TS
3
IC50 = 4580 nM
   TI
   LI
   LO
   TS
4
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 4 nM
2 Ki = 7 nM
3 Ki = 17 nM