Brief Information of the Compound and Protein
Compound Name
1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester;hydrobromide
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PubChem ID
CID: 2230
SID: 15219310
Canonical SMILES
COC(=O)C1=CCCN(C)C1
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Compound Formula C8H13NO2
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  4
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 4500 nM
   TI
   LI
   LO
   TS
3
Ki = 40 nM
   TI
   LI
   LO
   TS
4
Ki = 2454.71 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 25 nM
2 IC50 = 1800 nM
3 Ki = 2400 nM