Brief Information of the Compound and Protein
Compound Name
6-(5-Bromo-thiophen-2-ylmethoxy)-6,9-dihydro-1H-purin-2-ylamine
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PubChem ID
CID: 44366364
Canonical SMILES
NC1=Nc2nc[nH]c2C(N1)OCc1ccc(Br)s1
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Compound Formula C10H10BrN5OS
Compound Structure
Protein Name
Methylated-DNA--protein-cysteine methyltransferase
Protein Classification
Enzyme
Uniprot ID
P16455
Gene Name
MGMT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000174 Raji Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM