Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yl hydrogen (S)-1-((S)-1-(1H-indol-3-yl)-3-oxobutan-2-ylamino)-4-methyl-1-oxopentan-2-ylphosphoramidate
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 PubChem ID
CID: 445114
SID: 16163834
Canonical SMILES
CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
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Compound Formula C23H34N3O10P
Compound Structure
Protein Name
 Protein Info 
Endothelin-converting enzyme 1
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAE clan
>
Metallo protease M13 family
Uniprot ID
P42892
Gene Name
ECE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17 nM
2 IC50 = 800 nM
3 IC50 = 1200 nM
4 IC50 = 2000 nM