Brief Information of the Compound and Protein
Compound Name
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
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PubChem ID
CID: 53627818
SID: 15120660
Canonical SMILES
C[N+](C)(C)CCOC(N)=O.[Cl-]
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Compound Formula C6H15ClN2O2
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P08912
Gene Name
CHRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  3
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
2
EC50 = 6309.57 nM
   TI
   LI
   LO
   TS
3
Ki = 19952.62 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 25200 nM
   TI
   LI
   LO
   TS
2
Ki = 4265.8 nM
   TI
   LI
   LO
   TS
3
Ki = 69183.1 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3 Mus musculus (Mouse)  2
1
EC50 = 8900 nM
   TI
   LI
   LO
   TS
2
ED50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 360 nM
2 Ki = 4300 nM