Brief Information of the Compound and Protein
Compound Name
1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one
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PubChem ID
CID: 4932
SID: 14900354
Canonical SMILES
CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1
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Compound Formula C21H27NO3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000253 CCRF/VCR1000 Homo sapiens (Human)  2
1
EC50 = 320 nM
   TI
   LI
   LO
   TS
2
EC50 = 329 nM
   TI
   LI
   LO
   TS
CL001024 MDR CCRF vcr1000 Homo sapiens (Human)  1
1
EC50 = 331.13 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4200 nM