Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
    Show/Hide
 PubChem ID
CID: 5281040
SID: 14886896
Canonical SMILES
CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
    Show/Hide
Compound Formula C35H36ClNO3S
Compound Structure
Protein Name
 Protein Info 
Cysteinyl leukotriene receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Leukotriene receptor
Uniprot ID
Q9Y271
Gene Name
CYSLTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 72 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.78 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5 nM
2 IC50 = 2.3 nM