Brief Information of the Compound and Protein
Compound Name
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3,4-difluoro-phenyl)-1-{2-[(pentane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid
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PubChem ID
CID: 10650638
SID: 15682227
Canonical SMILES
CCCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(F)c(F)c1)C(O)=O)c1ccc2OCOc2c1
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Compound Formula C28H36F2N2O6S
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000304 MMQ Rattus norvegicus (Rat)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS