Brief Information of the Compound and Protein
Compound Name
4-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide
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PubChem ID
CID: 10737474
SID: 15773729
Canonical SMILES
Clc1ccc(cc1)C(=O)NCN1CCN(CC1)c1ccccc1Cl
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Compound Formula C18H19Cl2N3O
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 8.318 nM
   TI
   LI
   LO
   TS
CL001028 CHO Pro-5 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 8.4 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.248 nM