Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
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 PubChem ID
CID: 9975465
SID: 14953199
Canonical SMILES
Clc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N
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Compound Formula C19H19ClN4O
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.248 nM
   TI
   LI
   LO
   TS
CL001028 CHO Pro-5
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5.3 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 33.88 nM