Brief Information of the Compound and Protein
Compound Name
4-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
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PubChem ID
CID: 10473658
SID: 15497230
Canonical SMILES
COc1ccccc1N1CCN(CNC(=O)c2ccc(Cl)cc2)CC1
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Compound Formula C19H22ClN3O2
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.467 nM
   TI
   LI
   LO
   TS
CL001028 CHO Pro-5 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 8.4 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 14.13 nM