Brief Information of the Compound and Protein
Compound Name
(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-{[bis-(2-methoxy-ethyl)-carbamoyl]-methyl}-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
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PubChem ID
CID: 10625633
SID: 15656090
Canonical SMILES
COCCN(CCOC)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1
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Compound Formula C27H34N2O8
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000304 MMQ Rattus norvegicus (Rat)  1
1
IC50 = 4.45 nM
   TI
   LI
   LO
   TS