Brief Information of the Compound and Protein
Compound Name
2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pentanoylamino]-2-(1-ethyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid
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PubChem ID
CID: 10721386
SID: 15756564
Canonical SMILES
CCn1cc(C[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)NC2CCCCC2)c2nc(C(O)=O)c(C)[nH]2)c2ccccc12
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Compound Formula C30H42N6O4
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000304 MMQ Rattus norvegicus (Rat)  1
1
IC50 = 730 nM
   TI
   LI
   LO
   TS