Brief Information of the Compound and Protein
Compound Name
2-[(R)-1-{(S)-2-[3-(3-Fluoro-phenyl)-ureido]-4-methyl-pentanoylamino}-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid
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PubChem ID
CID: 44386535
Canonical SMILES
CC(C)C[C@H](NC(=O)Nc1cccc(F)c1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1
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Compound Formula C29H32FN5O5
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000304 MMQ Rattus norvegicus (Rat)  1
1
IC50 = 66 nM
   TI
   LI
   LO
   TS