Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
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 PubChem ID
CID: 60490
SID: 12014274
Canonical SMILES
CC(N(O)C(N)=O)c1cc2ccccc2s1
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Compound Formula C11H12N2O2S
Compound Structure
Protein Name
 Protein Info 
Polyunsaturated fatty acid 5-lipoxygenase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P12527
Gene Name
ALOX5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000194 RBL-1
 Cell Line Info 
Rattus norvegicus (Rat)  4
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
2
IC50 = 370 nM
   TI
   LI
   LO
   TS
3
IC50 = 600 nM
   TI
   LI
   LO
   TS
4
IC50 = 3200 nM
   TI
   LI
   LO
   TS
CL000278 RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat)  2
1
IC50 = 804 nM
   TI
   LI
   LO
   TS
2
IC50 = 1250 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 830 nM
2 IC50 = 3200 nM