Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride

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PubChem ID

CID: 53627818

SID: 15120660

Canonical SMILES	C[N+](C)(C)CCOC(N)=O.[Cl-] Show/Hide
Compound Formula	C6H15ClN2O2

Compound Structure

Protein Name

Protein Info

Muscarinic acetylcholine receptor M2

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Small molecule receptor (family A GPCR)

Monoamine receptor

Acetylcholine receptor

Uniprot ID

P08172

Gene Name

CHRM2

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000398	A-9 Cell Line Info	Mus musculus (Mouse)	2
1	IC50 = 12.59 nM	TI LI LO TS
2	Ki = 100 nM	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	9
1	EC50 = 700 nM	TI LI LO TS
2	EC50 = 61000 nM	TI LI LO TS
3	ED50 = 270 nM	TI LI LO TS
4	IC50 = 3.8 nM	TI LI LO TS
5	IC50 = 3460 nM	TI LI LO TS
6	Ki = 20 nM	TI LI LO TS
7	Ki = 38 nM	TI LI LO TS
8	Ki = 1230.27 nM	TI LI LO TS
9	Ki = 1318.26 nM	TI LI LO TS
CL001014	CHO-CHRM2 Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	EC50 = 700 nM	TI LI LO TS
CL000025	HEK-293T Cell Line Info	Homo sapiens (Human)	1
1	Ki = 4100 nM	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	EC50 = 107.15 nM	TI LI LO TS
CL000035	NIH 3T3 Cell Line Info	Mus musculus (Mouse)	1
1	ED50 = 22.8 nM	TI LI LO TS

Biochemical Assays