Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
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 PubChem ID
CID: 1220
SID: 14798544
Canonical SMILES
CCCN(CCC)C1CCc2cccc(O)c2C1
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Compound Formula C16H25NO
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
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Serotonin receptor
Uniprot ID
P19327
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.1 nM
2 IC50 = 2.1 nM
3 IC50 = 3 nM
4 IC50 = 8.06 nM
5 Kd = 2.5 nM
6 Ki = 0.47 nM
7 Ki = 0.5 nM
8 Ki = 1 nM
9 Ki = 1.2 nM
10 Ki = 1.44 nM
11 Ki = 1.59 nM
12 Ki = 2.1 nM
13 Ki = 4.3 nM
14 Ki = 8.7 nM