Brief Information of the Compound and Protein
Compound Name
(1-{(R)-1-{3-[(E)-2-(2-Chloro-thieno[3,2-b]pyridin-5-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid
    Show/Hide
PubChem ID
CID: 15290705
Canonical SMILES
CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(Cl)cc3n2)c1
    Show/Hide
Compound Formula C33H34ClNO3S2
Compound Structure
Protein Name
Cysteinyl leukotriene receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Leukotriene receptor
Uniprot ID
Q9Y271
Gene Name
CYSLTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 1.16 nM
   TI
   LI
   LO
   TS