Brief Information of the Compound and Protein
Compound Name
(1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyridin-5-yl)-vinyl]-phenyl}-3-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid
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PubChem ID
CID: 44319716
Canonical SMILES
OC(=O)CC1(CS[C@H](CCc2ccccc2C(O)(C(F)(F)F)C(F)(F)F)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1
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Compound Formula C33H27Cl2F6NO3S2
Compound Structure
Protein Name
Cysteinyl leukotriene receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Leukotriene receptor
Uniprot ID
Q9Y271
Gene Name
CYSLTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 6.42 nM
   TI
   LI
   LO
   TS