Brief Information of the Compound and Protein
Compound Name
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
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PubChem ID
CID: 1219
SID: 14847634
Canonical SMILES
CCCN(CCC)C1CCc2ccc(O)cc2C1
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Compound Formula C16H25NO
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000367 AtT-20 Mus musculus (Mouse)  1
1
EC50 = 0.531 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  6
1
Ki = 1.49 nM
   TI
   LI
   LO
   TS
2
Ki = 1.75 nM
   TI
   LI
   LO
   TS
3
Ki = 2.35 nM
   TI
   LI
   LO
   TS
4
Ki = 3.6 nM
   TI
   LI
   LO
   TS
5
Ki = 270 nM
   TI
   LI
   LO
   TS
6
Ki = 1400 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 2.9 nM
   TI
   LI
   LO
   TS