General Information of the Protein
Protein ID
PT07717
Protein Name
Prolactin-releasing peptide
Secondarily
Protein Name
Prolactin-releasing hormone
Gene Name
PRLH
Secondarily
Gene Name
PRH
Sequence
MKVLRAWLLCLLMLGLALRGAASRTHRHSMEIRTPDINPAWYASRGIRPVGRFGRRRATLGDVPKPGLRPRLTCFPLEGGAMSSQDG
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Organism
Homo sapiens, Human
Protein Classification
Secreted protein
Function
Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.
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Uniprot ID
P81277
Ensembl ID
ENSG00000071677
HGNC ID
HGNC:17945
Subcellular Location
Secreted
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0952756
 Compound Info 
(S)-4-((2S,3S)-1-((S)-1-((S)-2-((6S,9S,15S,18S,21S,24S,27S,30S)-27-((1H-indol-3-yl)methyl)-1-amino-6-((S)-2-((S)-1-(2-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-9-sec-butyl-15-(3-guanidinopropyl)-24-(4-hydroxybenzyl)-18-(hydroxymethyl)-1-imino-21-methyl-8,11,14,17,20,23,26,29-octaoxo-2,7,10,13,16,19,22,25,28-nonaazahentriacontan-30-ylcarbamoyl)pyrrolidin-1-yl)-4-amino-1,4-dioxobutan-2-ylamino)-3-methyl-1-oxopentan-2-ylamino)-3-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carboxamido)-4-oxobutanoic acid
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C104H158N32O26
  1
1
Ki = 2.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0496330
 Compound Info 
(2R)-N-[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)-2-(3,3-diphenylprop-2-enoylamino)pentanamide
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C30H34N6O3
  1
1
Ki > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528734
 Compound Info 
(2R)-N-(2-amino-2-oxoethyl)-5-(diaminomethylideneamino)-2-(3,3-diphenylprop-2-enoylamino)pentanamide
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C23H28N6O3
  1
1
Ki > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528735
 Compound Info 
(2S)-2-[[(2R)-5-(diaminomethylideneamino)-2-(3,3-diphenylprop-2-enoylamino)pentanoyl]amino]-4-methylpentanamide
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C27H36N6O3
  1
1
Ki > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS