General Information of the Protein
Protein ID
PT07698
Protein Name
Sodium-dependent phosphate transport protein 2C
Secondarily
Protein Name
Na(+)-dependent phosphate cotransporter 2C
Sodium/phosphate cotransporter 2C
Solute carrier family 34 member 3
Gene Name
SLC34A3
Sequence
MPNSLAGDQVPNPTLDAIGLVDWSLRNAGTSGSTPGLEEGGTDPWTFSQLKNTDQLKEVGTASKLHQVVSGFLKACGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVVVTVLVQSSSTSSSIVVSMVASKSLTVQASVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFGGSAVHGIFNWLTVLVLLPLENATAALERLSELALGAASLQPGGQAPDILKALTRPFTHLIIQLDSSVVTSSITSNTTNSSLIKHWCGFRGETPQGSSEECDLSGSCTERNSSASPGEDRLLCHHLFAGSELTDLAVGFILLAGSLLVLCVCLVLIVKLLNSVLRGRIAQAVKTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVINLERAYPLFLGSNIGTTTTALLAALASPADTLLFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGDLTAQYRWVAIVYLLLTFLLLPLAAFGLSLAGGSVLAAVGGPLVGLVLLIILVNVLQRHRPSWLPRRLQSWAWLPLWLHSLEPWDRLVTGCCPFKAYSNSHMTSKVAHCYENPQVIASQQL
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Organism
Rattus norvegicus, Rat
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC34 family of sodium phosphate co-transporters
Function
Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (PubMed:11880379). The cotransport has a Na(+):Pi stoichiometry of 2:1 and is electroneutral (By similarity).
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Uniprot ID
Q8K4R8
Ensembl ID
ENSG00000198569
Subcellular Location
Apical cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0432155
 Compound Info 
3-chloro-7-[(2S)-2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
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C15H14ClF3N4O2
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
90% Identity
Protein ID Protein Name Protein Organism
PT07431 Sodium-dependent phosphate transport protein 2C Mus musculus, Mouse
 Protein Info