General Information of the Protein
Protein ID
PT06789
Protein Name
Probable G-protein coupled receptor 139
Secondarily
Protein Name
G(q)-coupled orphan receptor GPRg1
Gene Name
GPR139
Secondarily
Gene Name
Gprg1
Sequence
MEHTHAHLAANSSACGLGFVPVVYYSFLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILTMQMPPIPDKIIEVLEFSSIHTSIWITVPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYITCFLTSIPYYWWPNIWTEDYISTSMHHVLVWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKHGKPIKVSP
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Organism
Rattus norvegicus, Rat
Protein Classification
Unclassified protein
Function
Orphan receptor. Seems to act through a G(q/11)-mediated pathway.
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Uniprot ID
P0C0W8
Ensembl ID
ENSG00000180269
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000026 , CHO-K1
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0868363
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-(4-methylpiperazin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
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C20H23ClFN7O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0868364
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-chloro-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C15H12Cl2FN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0868365
 Compound Info 
(S)-N-(1-(3-chloro-4-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C17H17ClN4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0868386
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-morpholino-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C19H20ClFN6O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0868389
 Compound Info 
(S)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C18H20N4O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0868397
 Compound Info 
(S)-2-(3-oxo-5-(piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C22H24F3N5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0868429
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C16H14ClFN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870162
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H15ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870163
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-methyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H15ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870164
 Compound Info 
(S)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H16F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870165
 Compound Info 
(S)-2-(5-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C17H17FN4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870166
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-chloro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C16H13Cl2FN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870167
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-cyano-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C17H13ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870168
 Compound Info 
(S)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(3-fluoro-4-methylphenyl)ethyl)acetamide
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C17H16F2N4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870175
 Compound Info 
2-(7-((R)-3-hydroxypiperidin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-((S)-1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C22H24F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870178
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(5,7-dimethyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C17H17ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870298
 Compound Info 
(S)-2-(8-((2,2-difluoroethyl)amino)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C19H21F2N5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870300
 Compound Info 
(S)-N-(1-(3-fluoro-4-(trifluoromethoxy)phenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H13F4N5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870301
 Compound Info 
(S)-2-(6-chloro-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C16H13ClF3N5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870302
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C15H13ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870303
 Compound Info 
(S)-N-(1-(3,4-dichlorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C16H14Cl2N4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870306
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-(oxetan-3-ylamino)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C19H19ClFN5O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870311
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H15ClFN5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870314
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C17H18N4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870328
 Compound Info 
(S)-2-(8-amino-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C17H19N5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870330
 Compound Info 
(S)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H14F4N4O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870331
 Compound Info 
(S)-2-(5-(3-hydroxyazetidin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C20H20F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870332
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(5-morpholino-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C20H21ClFN5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0870333
 Compound Info 
(S)-2-(7-(4-hydroxypiperidin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C22H24F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0871619
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C16H13ClF2N4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0882473
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C15H13ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0882481
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-cyclopropyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C18H17ClFN5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0882483
 Compound Info 
(S)-N-(1-(3-fluoro-4-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C16H16FN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0882488
 Compound Info 
(S)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethyl)phenyl)ethyl)acetamide
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C17H14F4N4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0882489
 Compound Info 
(S)-2-(7-(oxetan-3-yloxy)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C20H19F3N4O5
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0887598
 Compound Info 
(S)-2-(7-(4-methoxypiperidin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C23H26F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0887600
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C16H17N5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0887602
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-chloro-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C15H12Cl2FN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0887603
 Compound Info 
(S)-2-(7-chloro-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C16H13ClF3N5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0887623
 Compound Info 
(S)-N-(1-(4-chloro-2-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H16ClN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0898608
 Compound Info 
(S)-2-(8-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C18H20N4O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0898609
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-methoxy-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H15ClFN5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0898611
 Compound Info 
(S)-2-(8-(methylamino)-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H17F3N6O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0898647
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-cyclopropyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C18H17ClFN5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0903305
 Compound Info 
(S)-N-(1-(3-fluoro-4-methylphenyl)ethyl)-2-(8-methyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C17H18FN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903316
 Compound Info 
(S)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C17H19N5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903319
 Compound Info 
(S)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C18H17F3N4O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0903320
 Compound Info 
(S)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C18H20N4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0903344
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-iodo-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C15H12ClFIN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903345
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)propyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H15ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903346
 Compound Info 
(S)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C17H19N5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903351
 Compound Info 
(S)-N-(1-(4-chloro-2-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C17H17ClN4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903352
 Compound Info 
(S)-2-(6-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C18H17F3N4O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0903353
 Compound Info 
2-(7-((S)-3-hydroxypiperidin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-((S)-1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C22H24F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0911968
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-8-(piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
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C20H22ClFN6O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0911969
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C17H16ClFN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0914628
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C16H14ClFN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0914629
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C15H12ClF2N5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0914630
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C17H15F3N4O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0914631
 Compound Info 
(S)-2-(5-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C18H17F3N4O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0914632
 Compound Info 
(S)-N-(1-(3,4-dichlorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C15H13Cl2N5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0914633
 Compound Info 
(S)-N-(1-(4-chloro-3-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H16ClN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0914714
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H16ClN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0928247
 Compound Info 
(S)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C17H17FN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0928248
 Compound Info 
(S)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C18H17F3N4O4
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0928249
 Compound Info 
(S)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C18H17F3N4O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0942934
 Compound Info 
N-((S)-1-(4-chloro-3-fluorophenyl)ethyl)-2-(5-(3-methylmorpholino)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C21H23ClFN5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0942936
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-morpholino-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C20H21ClFN5O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0943033
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methoxy-6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C17H17ClFN5O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0943680
 Compound Info 
(S)-2-(8-((2,2-difluoroethyl)amino)-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C18H17F5N6O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0943681
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
   Show/Hide
C15H13ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0943685
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(5-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C17H17ClN4O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0943688
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-chloro-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C15H12Cl2FN5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0943693
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethyl)phenyl)ethyl)acetamide
   Show/Hide
C17H15F3N4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0943697
 Compound Info 
(S)-N-(1-(4-(difluoromethoxy)-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C17H15F3N4O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0943701
 Compound Info 
(S)-2-(6-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C18H20N4O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0944300
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C16H15ClFN5O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0944921
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C17H16ClFN4O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0944922
 Compound Info 
(S)-2-(5-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C18H20N4O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0952677
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)-2-methylpropyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C17H17ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0954292
 Compound Info 
(S)-N-(1-(4-cyclopropyl-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C18H18FN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0954293
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7,8-dimethyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C17H17ClFN5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0954296
 Compound Info 
(S)-2-(8-chloro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C17H17ClN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0955703
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C22H18ClFN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0955713
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C16H15ClFN5O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0955715
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C16H16ClN5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0955716
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-cyano-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C17H13ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0955718
 Compound Info 
(S)-2-(7-morpholino-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C21H22F3N5O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0955719
 Compound Info 
(S)-N-(1-(3-chloro-4-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C16H16ClN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0955720
 Compound Info 
(R)-N-((S)-1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)propanamide
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C16H15ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0955722
 Compound Info 
(S)-2-(3-oxo-7-(piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C22H24F3N5O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0956031
 Compound Info 
(S)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C18H20N4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0956045
 Compound Info 
(S)-2-(7-chloro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(5-fluoro-6-methylpyridin-3-yl)ethyl)acetamide
   Show/Hide
C16H15ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0956049
 Compound Info 
(S)-2-(8-(methylamino)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C18H21N5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0957611
 Compound Info 
(S)-2-(8-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C17H17FN4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0958445
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C16H15ClFN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0958448
 Compound Info 
(S)-2-(7-chloro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C17H17ClN4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0958688
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
   Show/Hide
C16H15ClFN5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0958689
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-(oxetan-3-ylamino)-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
   Show/Hide
C18H18ClFN6O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0958693
 Compound Info 
(S)-2-(6-bromo-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C17H17BrN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0958694
 Compound Info 
(S)-2-(8-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C17H16F3N5O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0960975
 Compound Info 
(S)-N-(1-(4-chloro-3-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C17H17ClN4O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0961050
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-(oxetan-3-ylamino)-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C18H18ClFN6O3
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0962195
 Compound Info 
(S)-2-(7-chloro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C17H14ClF3N4O3
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0962196
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-iodo-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C16H13ClFIN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0962207
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-(methylamino)-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
   Show/Hide
C16H16ClFN6O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0962208
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C16H15ClN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0963502
 Compound Info 
(S)-N-(1-(3-fluoro-4-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C16H16FN5O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0964630
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(5-(3,3-difluoroazetidin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C19H17ClF3N5O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0967444
 Compound Info 
(R)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C16H14ClFN4O2
  1
1
EC50 < 1 nM
 Bioactivity Info 
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CP0870174
 Compound Info 
(S)-N-(1-(4-cyclopropyl-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C18H18FN5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0870308
 Compound Info 
N-(1-(4-(difluoromethoxy)phenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C17H16F2N4O3
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0870309
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-(6-methyl-1,6-diazaspiro[3.3]heptan-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C22H24ClFN6O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0870310
 Compound Info 
(S)-N-(1-(4-cyclopropylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C18H19N5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0882485
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(6-cyclopropyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C18H17ClFN5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0887599
 Compound Info 
(S)-N-(1-mesitylethyl)-2-(7-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C20H24N4O3
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0887604
 Compound Info 
(S)-2-(8-iodo-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C16H13F3IN5O3
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0903303
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
   Show/Hide
C15H14ClN5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0943682
 Compound Info 
(S)-N-(1-(3,4-dichlorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C15H13Cl2N5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0943683
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(5-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C16H15ClFN5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0943687
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C16H14F3N5O3
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0944302
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-8-(1,6-diazaspiro[3.3]heptan-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C21H22ClFN6O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0955712
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(3-oxo-8-(piperazin-1-yl)-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
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C19H21ClFN7O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0958446
 Compound Info 
(S)-N-(1-(3-fluoro-4-(trifluoromethoxy)phenyl)ethyl)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C17H15F4N5O3
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0966350
 Compound Info 
(S)-N-(1-(3-chloro-4-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C16H16ClN5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
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CP0868395
 Compound Info 
(S)-2-(8-(oxetan-3-ylamino)-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C19H19F3N6O4
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0868396
 Compound Info 
(S)-2-(6-methoxy-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H16F3N5O4
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0870171
 Compound Info 
(S)-N-(1-(3-fluoro-4-(trifluoromethoxy)phenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C16H13F4N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0870177
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C15H13ClFN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0870299
 Compound Info 
2-(3-oxo-8-(pyrrolidin-3-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-((S)-1-(p-tolyl)ethyl)acetamide
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C21H25N5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0870312
 Compound Info 
(S)-2-(3-oxo-6-(piperidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C21H23F3N6O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0870313
 Compound Info 
(S)-2-(5-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H16F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0882478
 Compound Info 
N-(1-(4-chlorophenyl)cyclopropyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H14ClN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0887597
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(5-(4-methylpiperazin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C21H24ClFN6O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0887601
 Compound Info 
(S)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H16F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903218
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
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C16H17N5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903313
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(6-methoxy-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H16ClN5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903315
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C15H14ClN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903317
 Compound Info 
(S)-N-(1-(4-isopropoxyphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C19H22N4O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903318
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)acetamide
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C15H13F3N6O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903347
 Compound Info 
(S)-N-(1-(4-chloro-2-methylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C16H16ClN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0903354
 Compound Info 
2-(8-(1-methylpyrrolidin-3-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-((S)-1-(p-tolyl)ethyl)acetamide
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C22H27N5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0914624
 Compound Info 
N-(1-(3-chlorophenyl)cyclopropyl)-2-(3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)acetamide
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C16H14ClN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0914625
 Compound Info 
(S)-N-(1-(4-(difluoromethoxy)-3-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C16H14F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0914626
 Compound Info 
(S)-N-(1-(4-cyclopropylphenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
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C18H19N5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0922696
 Compound Info 
(S)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H16F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0922697
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(7-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C16H15ClFN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0942927
 Compound Info 
(S)-2-(8-(difluoromethyl)-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C17H14F5N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0942938
 Compound Info 
(S)-N-(1-(4-fluorophenyl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C16H15FN4O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0942939
 Compound Info 
N-(1-(3-chlorophenyl)cyclopropyl)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C17H14ClFN4O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0943678
 Compound Info 
(S)-N-(1-(4-chloro-3-fluorophenyl)ethyl)-2-(8-((1-methylazetidin-3-yl)oxy)-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide
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C19H20ClFN6O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0943686
 Compound Info 
(S)-2-(5-(4-methylpiperazin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C22H25F3N6O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0944920
 Compound Info 
N-(1-(5-chloro-3-fluoropyridin-2-yl)ethyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
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C15H13ClFN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0954290
 Compound Info 
(S)-2-(7-(4-methylpiperazin-1-yl)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C22H25F3N6O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0955702
 Compound Info 
(S)-2-(6-cyclopropyl-3-oxo-[1,2,4]triazolo[4,3-b]pyridazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
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C19H18F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0955714
 Compound Info 
(S)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C17H16F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0955717
 Compound Info 
(S)-2-(3-oxo-5-(piperazin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C21H23F3N6O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0956046
 Compound Info 
N-(1-(4-chlorophenyl)cyclopropyl)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)acetamide
   Show/Hide
C17H14ClFN4O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0956047
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(5,7-dimethyl-3-oxo-[1,2,4]triazolo[4,3-c]pyrimidin-2(3H)-yl)acetamide
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C17H18ClN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0956048
 Compound Info 
(S)-2-(6-fluoro-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C16H13F4N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0958447
 Compound Info 
(S)-N-(1-(4-chlorophenyl)ethyl)-2-(5,7-dimethyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide
   Show/Hide
C17H18ClN5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0958695
 Compound Info 
(S)-2-(6-methyl-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C17H16F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0958696
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C16H14F3N5O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0960360
 Compound Info 
(S)-2-(8-(azetidin-3-yloxy)-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)-N-(1-(4-chloro-3-fluorophenyl)ethyl)acetamide
   Show/Hide
C18H18ClFN6O3
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0961754
 Compound Info 
(S)-2-(7-((1-methylazetidin-3-yl)oxy)-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide
   Show/Hide
C21H22F3N5O4
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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CP0962194
 Compound Info 
(S)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)-N-(1-(p-tolyl)ethyl)acetamide
   Show/Hide
C16H17N5O2
  1
1
EC50 >= 100 nM
 Bioactivity Info 
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Similar Protein(s) and Bioactivity Statistics
90% Identity
Protein ID Protein Name Protein Organism
PT06277 Probable G-protein coupled receptor 139 Homo sapiens, Human
 Protein Info