Protein Information

General Information of the Protein

Protein ID	PT06200
Protein Name	Scavenger receptor class B member 1
Secondarily Protein Name	SR-BI
Gene Name	SCARB1
Secondarily Gene Name	Srb1
Sequence	MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIICQLRSQEKCFLFWSGSKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL Show/Hide
Organism	Mus musculus, Mouse
Protein Classification	Membrane receptor
Function	Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (By similarity). Both isoform 1 and isoform 2 act as receptors for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:9254074, PubMed:9614139). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity). Show/Hide
Uniprot ID	Primary ID: Q61009 Secondarily ID: D3Z2V4 Q3TZ42 Q4FK30 Q9CWJ7 Show/Hide
Ensembl ID	ENSG00000073060
Subcellular Location	Cell membrane Membrane Caveola

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000011 , CHO

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0379524 Compound Info	(2R)-2-[[2-[5-(1,3-benzodioxol-5-yl)tetrazol-2-yl]acetyl]-cyclohexylamino]-N-cyclopentylpropanamide Show/Hide	C24H32N6O4	3
1	EC50 = 270 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5 nM Bioactivity Info	TI LI LO TS
3	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0411345 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylurea Show/Hide	C26H35ClN4O6S	3
1	EC50 = 400 nM Bioactivity Info	TI LI LO TS
2	IC50 = 60 nM Bioactivity Info	TI LI LO TS
3	IC50 = 250 nM Bioactivity Info	TI LI LO TS
CP0379305 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)-1,2-oxazol-3-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C27H37N3O5	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0499296 Compound Info	2-[5-(1,3-benzodioxol-5-yl)tetrazol-2-yl]-N-cyclohexyl-N-[2-(cyclopentylamino)-2-oxoethyl]acetamide Show/Hide	C23H30N6O4	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0546474 Compound Info	2-[[2-[5-(1,3-benzodioxol-5-yl)tetrazol-2-yl]acetyl]-cyclohexylamino]-N-cyclopentylpropanamide Show/Hide	C24H32N6O4	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0487068 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclohexanecarboxamide Show/Hide	C29H38ClN3O6S	1
1	IC50 = 54 nM Bioactivity Info	TI LI LO TS
CP0500646 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C25H36N6O4	1
1	IC50 = 55 nM Bioactivity Info	TI LI LO TS
CP0479928 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-(4-fluorophenyl)urea Show/Hide	C29H32ClFN4O6S	1
1	IC50 = 92 nM Bioactivity Info	TI LI LO TS
CP0519390 Compound Info	N-cyclopentyl-2-[cyclopentyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]propanamide Show/Hide	C24H34N6O4	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0548352 Compound Info	2-[cyclohexyl-[2-[5-(4-fluorophenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C23H31FN6O2	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0571269 Compound Info	2-[cyclohexyl-[2-[2-(3,4-dimethoxyphenyl)-1,3-oxazol-4-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C27H37N3O5	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0499298 Compound Info	2-[[2-[5-(4-chlorophenyl)tetrazol-2-yl]acetyl]-cyclohexylamino]-N-cyclopentylpropanamide Show/Hide	C23H31ClN6O2	1
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0441246 Compound Info	N-[(2R,3R)-2-[[(2-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclohexanecarboxamide Show/Hide	C29H38ClN3O6S	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0481888 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0497911 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dichlorophenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C23H30Cl2N6O2	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0514665 Compound Info	2-[cyclohexyl-[2-[5-(3-methoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C24H34N6O3	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0481938 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide Show/Hide	C27H33ClN4O8S2	1
1	IC50 = 190 nM Bioactivity Info	TI LI LO TS
CP0514667 Compound Info	N-cyclohexyl-2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]propanamide Show/Hide	C26H38N6O4	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0571449 Compound Info	N-[(2R,3R)-2-[[benzenesulfonyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H38N4O6S	1
1	IC50 = 220 nM Bioactivity Info	TI LI LO TS
CP0525352 Compound Info	2-[cyclohexyl-[2-[5-(2,2-difluoro-1,3-benzodioxol-5-yl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C24H30F2N6O4	1
1	IC50 = 230 nM Bioactivity Info	TI LI LO TS
CP0510412 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4,4,4-trifluorobutanamide Show/Hide	C26H31ClF3N3O6S	1
1	IC50 = 260 nM Bioactivity Info	TI LI LO TS
CP0487041 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea Show/Hide	C30H35ClN4O7S	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0413855 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-cyclohexylurea Show/Hide	C29H39ClN4O6S	1
1	IC50 = 350 nM Bioactivity Info	TI LI LO TS
CP0499297 Compound Info	2-[cyclohexyl-[2-(5-phenyltetrazol-2-yl)acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C23H32N6O2	1
1	IC50 = 370 nM Bioactivity Info	TI LI LO TS
CP0546476 Compound Info	2-[cyclohexyl-[2-[5-(3-fluorophenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C23H31FN6O2	1
1	IC50 = 380 nM Bioactivity Info	TI LI LO TS
CP0556259 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopropylpropanamide Show/Hide	C23H32N6O4	1
1	IC50 = 420 nM Bioactivity Info	TI LI LO TS
CP0546475 Compound Info	2-[cyclohexyl-[2-[5-(4-methylphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C24H34N6O2	1
1	IC50 = 490 nM Bioactivity Info	TI LI LO TS
CP0455879 Compound Info	N-[(2R,3R)-2-[[(4-fluorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37FN4O6S	1
1	IC50 = 560 nM Bioactivity Info	TI LI LO TS
CP0397935 Compound Info	2-[cyclohexyl-[2-[5-(2-fluorophenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C23H31FN6O2	1
1	IC50 = 620 nM Bioactivity Info	TI LI LO TS
CP0487040 Compound Info	4-chloro-N-[[(2R,3R)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-N-methylbenzenesulfonamide Show/Hide	C24H32ClN3O5S	1
1	IC50 = 630 nM Bioactivity Info	TI LI LO TS
CP0491258 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C35H39F3N4O4	1
1	IC50 = 650 nM Bioactivity Info	TI LI LO TS
CP0949799 Compound Info	N-(5-tert-butyl-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide hydrochloride Show/Hide	C30H38ClN3O7S	1
1	IC50 = 770 nM Bioactivity Info	TI LI LO TS
CP0278504 Compound Info	N-[5-tert-butyl-3-(methanesulfonamido)-2-methoxyphenyl]-2-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]-2-oxoacetamide Show/Hide	C30H37N3O7S	1
1	IC50 = 770 nM Bioactivity Info	TI LI LO TS
CP0397936 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-propan-2-ylpropanamide Show/Hide	C23H34N6O4	1
1	IC50 = 810 nM Bioactivity Info	TI LI LO TS
CP0561079 Compound Info	2-[[2-[5-(1,3-benzodioxol-5-yl)tetrazol-2-yl]acetyl]-(oxan-4-yl)amino]-N-cyclopentylpropanamide Show/Hide	C23H30N6O5	1
1	IC50 = 840 nM Bioactivity Info	TI LI LO TS
CP0557161 Compound Info	N-[(2R,3R)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C35H40N4O6	1
1	IC50 = 890 nM Bioactivity Info	TI LI LO TS
CP0487020 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 = 910 nM Bioactivity Info	TI LI LO TS
CP0561080 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(pyridin-4-ylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H39N5O4	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0413136 Compound Info	4-chloro-N-[[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-8-(methanesulfonamido)-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-N-methylbenzenesulfonamide Show/Hide	C23H30ClN3O7S2	1
1	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0499755 Compound Info	N-[(2R,3R)-2-[[benzyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C34H40N4O4	1
1	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0488367 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentyl-N-methylpropanamide Show/Hide	C26H38N6O4	1
1	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0546472 Compound Info	(2S)-2-[[2-[5-(1,3-benzodioxol-5-yl)tetrazol-2-yl]acetyl]-cyclohexylamino]-N-cyclopentylpropanamide Show/Hide	C24H32N6O4	1
1	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0546473 Compound Info	2-[cyclohexylmethyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C26H38N6O4	1
1	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0555854 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-2-[[(4-methoxyphenyl)sulfonyl-methylamino]methyl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C34H40N4O7S	1
1	IC50 = 2000 nM Bioactivity Info	TI LI LO TS
CP0510411 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclopropanecarboxamide Show/Hide	C26H32ClN3O6S	1
1	IC50 = 2100 nM Bioactivity Info	TI LI LO TS
CP0441249 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(thiophen-2-ylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C31H36N4O6S2	1
1	IC50 = 2400 nM Bioactivity Info	TI LI LO TS
CP0564980 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-2-[[(4-methoxyphenyl)methyl-methylamino]methyl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C35H42N4O5	1
1	IC50 = 2600 nM Bioactivity Info	TI LI LO TS
CP0397907 Compound Info	N-[[(2R,3R)-8-(benzenesulfonamido)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-4-chloro-N-methylbenzenesulfonamide Show/Hide	C28H32ClN3O7S2	1
1	IC50 = 3200 nM Bioactivity Info	TI LI LO TS
CP0546477 Compound Info	2-[[2-[5-(2-chlorophenyl)tetrazol-2-yl]acetyl]-cyclohexylamino]-N-cyclopentylpropanamide Show/Hide	C23H31ClN6O2	1
1	IC50 = 3800 nM Bioactivity Info	TI LI LO TS
CP0441248 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(phenylcarbamoyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C34H39N5O5	1
1	IC50 = 4900 nM Bioactivity Info	TI LI LO TS
CP0487069 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-morpholin-4-ylpropanamide Show/Hide	C29H39ClN4O7S	1
1	IC50 = 5000 nM Bioactivity Info	TI LI LO TS
CP0547402 Compound Info	2-[cyclohexyl-[2-[2-(3,4-dimethoxyphenyl)-1,3-thiazol-4-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C27H37N3O4S	1
1	IC50 = 6300 nM Bioactivity Info	TI LI LO TS
CP0559296 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(1-methylimidazol-4-yl)sulfonylamino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C31H38N6O6S	1
1	IC50 = 6400 nM Bioactivity Info	TI LI LO TS
CP0549446 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-(3,5-dimethyl-1,2-oxazol-4-yl)urea Show/Hide	C28H34ClN5O7S	1
1	IC50 = 7100 nM Bioactivity Info	TI LI LO TS
CP0555298 Compound Info	N-cyclohexyl-2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]-N-(1-oxo-1-piperidin-1-ylpropan-2-yl)acetamide Show/Hide	C25H36N6O4	1
1	IC50 = 7100 nM Bioactivity Info	TI LI LO TS
CP0548351 Compound Info	N-cyclopentyl-2-[cyclopropyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]propanamide Show/Hide	C22H30N6O4	1
1	IC50 = 7500 nM Bioactivity Info	TI LI LO TS
CP0549445 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-methoxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylurea Show/Hide	C27H37ClN4O6S	1
1	IC50 = 8000 nM Bioactivity Info	TI LI LO TS
CP0487071 Compound Info	N-[(2S,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 = 8900 nM Bioactivity Info	TI LI LO TS
CP0472316 Compound Info	N-[(2R,3R)-2-[[cyclohexylmethyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C34H46N4O4	1
1	IC50 = 9200 nM Bioactivity Info	TI LI LO TS
CP0542139 Compound Info	N-[(2R,3R)-2-[[cyclohexylcarbamoyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C34H45N5O5	1
1	IC50 = 9200 nM Bioactivity Info	TI LI LO TS
CP0413137 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C28H36N4O6S	1
1	IC50 = 9900 nM Bioactivity Info	TI LI LO TS
CP0441245 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-3-methyl-6-oxo-5-propan-2-yl-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylurea Show/Hide	C26H35ClN4O5S	1
1	IC50 = 9900 nM Bioactivity Info	TI LI LO TS
CP0468256 Compound Info	N-[(2S,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0560932 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(tetrazol-1-yl)acetamide Show/Hide	C25H30ClN7O6S	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0510413 Compound Info	N-[(2R,3S)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 = 12300 nM Bioactivity Info	TI LI LO TS
CP0413135 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-fluorobenzenesulfonamide Show/Hide	C28H31ClFN3O7S2	1
1	IC50 = 14000 nM Bioactivity Info	TI LI LO TS
CP0547403 Compound Info	N-tert-butyl-2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]propanamide Show/Hide	C24H36N6O4	1
1	IC50 = 17000 nM Bioactivity Info	TI LI LO TS
CP0555855 Compound Info	N-[(2S,3S)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 = 17400 nM Bioactivity Info	TI LI LO TS
CP0555853 Compound Info	N-[(2R,3R)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C28H36N4O4	1
1	IC50 = 18000 nM Bioactivity Info	TI LI LO TS
CP0398512 Compound Info	N-cyclopentyl-2-[[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]-methylamino]propanamide Show/Hide	C20H28N6O4	1
1	IC50 = 19000 nM Bioactivity Info	TI LI LO TS
CP0555296 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentyl-2-methylpropanamide Show/Hide	C26H38N6O4	1
1	IC50 = 19000 nM Bioactivity Info	TI LI LO TS
CP0397300 Compound Info	4-chloro-N-[[(2R,3R)-8-(cyclohexanecarbonylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-N-methylbenzamide Show/Hide	C30H38ClN3O5	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0397908 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-(dimethylamino)butanamide Show/Hide	C28H39ClN4O6S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0413134 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-(dimethylamino)propan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C35H42ClN5O5S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0444227 Compound Info	N-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]oxane-4-carboxamide Show/Hide	C28H36ClN3O7S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0468255 Compound Info	N-[(2R,3R)-2-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C34H38Cl2N4O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0542502 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-3-propan-2-ylurea Show/Hide	C26H35ClN4O6S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0542503 Compound Info	1-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-phenylurea Show/Hide	C29H33ClN4O6S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0554736 Compound Info	N-[(2R,3R)-5-[(2R)-1-aminopropan-2-yl]-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H38ClN5O5S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0560934 Compound Info	N-[(2R,3S)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C33H37ClN4O6S	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0570893 Compound Info	N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methylindol-3-yl)acetamide Show/Hide	C27H34N4O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0397934 Compound Info	2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentyl-3-methylbutanamide Show/Hide	C27H40N6O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0548350 Compound Info	N-cyclopentyl-2-[[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]-(1-methylpiperidin-4-yl)amino]propanamide Show/Hide	C25H37N7O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0549192 Compound Info	2-[cyclohexyl-[2-[5-(2-methoxyphenyl)tetrazol-2-yl]acetyl]amino]-N-cyclopentylpropanamide Show/Hide	C24H34N6O3	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0514666 Compound Info	2-[cyclohexyl-(2-phenylacetyl)amino]-N-cyclopentylpropanamide Show/Hide	C22H32N2O2	1
1	IC50 = 37000 nM Bioactivity Info	TI LI LO TS
CP0397301 Compound Info	N-[(2R,3R)-2-[[(3-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclohexanecarboxamide Show/Hide	C29H38ClN3O6S	1
1	IC50 > 800 nM Bioactivity Info	TI LI LO TS

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About MolBiC

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Prof. Feng ZHU

Prof. Leo, Lianyi Han