General Information of the Protein
Protein ID
PT03750
Protein Name
Probable G-protein coupled receptor 142
Gene Name
GPR142
Sequence
MHLNSNPNSYICDAYQHADLLWSLSPHVLTKAVQPQVTLLPTVNGSNPRYDGVDGHWPESPERSPCVAGIIPVIYYSVLLSLGLPVALARLAARTRKPSYHYLLALTASDIVTQVIIVFVGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPGRTHRAIAAVIGVTLLTGIPFYWWLDVWRDADPPSTMDKLLKWAHCLIVYFIPCNVFLVTNSAIILRLRKRGQRGLRPLVSKSTAILLGVTSLFALLWAPRIIVMLYHLYVAPVHRDWRVHLALDIANMLAMLNTEVNFGLYCFISKTFRATVRQVICDVHMACALKSQPKQTVVELMLKSVGTEL
    Show/Hide
Organism
Mus musculus, Mouse
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Function
Orphan receptor.
    Show/Hide
Uniprot ID
Q7TQN9
Ensembl ID
ENSG00000257008
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0155419
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-[6-(2-methylimidazol-1-yl)pyridin-3-yl]triazol-1-yl]acetamide
   Show/Hide
C19H15Cl2N7O
  2
1
EC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0155420
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-[4-(2-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C20H16Cl2N6O
  2
1
EC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 27 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475865
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-(4-imidazol-1-ylphenyl)triazol-1-yl]acetamide
   Show/Hide
C19H14Cl2N6O
  2
1
EC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0094466
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-[3-fluoro-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C20H15Cl2FN6O
  2
1
EC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 78 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0432996
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-[4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C20H16Cl2N6O
  2
1
EC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419296
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-[2-fluoro-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C20H15Cl2FN6O
  2
1
EC50 = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 687 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0008174
 Compound Info 
2-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-N-naphthalen-1-ylacetamide
   Show/Hide
C25H22N6O2
  2
1
EC50 = 23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419292
 Compound Info 
N-(2,3-dichlorophenyl)-2-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C21H18Cl2N6O2
  2
1
EC50 = 36 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 198 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0433029
 Compound Info 
N-(2,3-dimethylphenyl)-2-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C23H24N6O2
  1
1
EC50 = 80 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419293
 Compound Info 
N-(2,3-dichlorophenyl)-2-methyl-2-[4-[4-(2-methylimidazol-1-yl)phenyl]triazol-1-yl]propanamide
   Show/Hide
C22H20Cl2N6O
  1
1
EC50 = 801 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0432997
 Compound Info 
N-(2,3-dichlorophenyl)-N-methyl-2-[4-[4-(2-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide
   Show/Hide
C21H18Cl2N6O
  1
1
EC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558267
 Compound Info 
N-(3-chloro-2-fluorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H17ClFN3O2
  1
1
IC50 = 59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0490372
 Compound Info 
N-(3-phenylphenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C27H23N3O2
  1
1
IC50 = 62 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421603
 Compound Info 
N-(3-cyanophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C22H18N4O2
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0500791
 Compound Info 
N-(2-methoxyphenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C22H21N3O3
  1
1
IC50 = 92 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560535
 Compound Info 
7-pyridin-4-yl-N-[3-(trifluoromethyl)phenyl]-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C22H18F3N3O2
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421600
 Compound Info 
N-(3,4-dichlorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H17Cl2N3O2
  1
1
IC50 = 138 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421602
 Compound Info 
N-(3-phenoxyphenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C27H23N3O3
  1
1
IC50 = 146 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466147
 Compound Info 
7-pyridin-4-yl-4-[[3-(trifluoromethyl)phenyl]methylsulfonyl]-3,5-dihydro-2H-1,4-benzoxazepine
   Show/Hide
C22H19F3N2O3S
  1
1
IC50 = 157 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568468
 Compound Info 
N-(2,3-dichlorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H17Cl2N3O2
  1
1
IC50 = 157 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421597
 Compound Info 
N-(3,4-dichlorophenyl)-7-pyridin-4-yl-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxamide
   Show/Hide
C21H18Cl2N4O
  1
1
IC50 = 158 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466150
 Compound Info 
N-(3-chlorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H18ClN3O2
  1
1
IC50 = 164 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466145
 Compound Info 
N-(3-methoxyphenyl)-7-quinolin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C26H23N3O3
  1
1
IC50 = 216 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560537
 Compound Info 
N-(3-methoxyphenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C22H21N3O3
  1
1
IC50 = 305 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560536
 Compound Info 
N-(3-fluorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H18FN3O2
  1
1
IC50 = 413 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0500790
 Compound Info 
7-(2-aminopyridin-4-yl)-N-(3-cyanophenyl)-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C22H19N5O2
  1
1
IC50 = 448 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546100
 Compound Info 
N-(3-methoxyphenyl)-7-(3-methoxypyridin-4-yl)-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C23H23N3O4
  1
1
IC50 = 486 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421595
 Compound Info 
N-(3,4-dichlorophenyl)-8-pyridin-4-yl-1,3,4,5-tetrahydro-2-benzazepine-2-carboxamide
   Show/Hide
C22H19Cl2N3O
  1
1
IC50 = 590 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564323
 Compound Info 
N-(2-fluorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H18FN3O2
  1
1
IC50 = 604 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466149
 Compound Info 
1-(7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl)-2-[3-(trifluoromethyl)phenyl]ethanone
   Show/Hide
C23H19F3N2O2
  1
1
IC50 = 611 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497286
 Compound Info 
N-(3-chloro-4-fluorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H17ClFN3O2
  1
1
IC50 = 613 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421604
 Compound Info 
N-phenyl-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H19N3O2
  1
1
IC50 = 851 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558266
 Compound Info 
N-(3,4-dichlorophenyl)-7-pyridin-4-yl-3,4-dihydro-1H-isoquinoline-2-carboxamide
   Show/Hide
C21H17Cl2N3O
  1
1
IC50 = 1050 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0485432
 Compound Info 
N-(3-methoxyphenyl)-7-(3-methylpyridin-4-yl)-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C23H23N3O3
  1
1
IC50 = 1180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421599
 Compound Info 
N-(3,4-dichlorophenyl)-1-methyl-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
   Show/Hide
C22H20Cl2N4O
  1
1
IC50 = 2570 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549438
 Compound Info 
N-(3-methoxyphenyl)-7-(2-methoxypyridin-4-yl)-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C23H23N3O4
  1
1
IC50 = 2570 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466148
 Compound Info 
N-(4-fluorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C21H18FN3O2
  1
1
IC50 = 2610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546101
 Compound Info 
N-(3,4-dichlorophenyl)-6-pyridin-4-yl-2,3-dihydroindole-1-carboxamide
   Show/Hide
C20H15Cl2N3O
  1
1
IC50 = 2950 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497287
 Compound Info 
1-butyl-N-(3,4-dichlorophenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
   Show/Hide
C25H26Cl2N4O
  1
1
IC50 = 4500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421598
 Compound Info 
N-(3,4-dichlorophenyl)-5-pyridin-4-yl-1,3-dihydroisoindole-2-carboxamide
   Show/Hide
C20H15Cl2N3O
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421601
 Compound Info 
N-(3-methoxyphenyl)-N-methyl-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C23H23N3O3
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466146
 Compound Info 
N-(3,4-dichlorophenyl)-7-pyridin-4-yl-3,4-dihydro-2H-quinoline-1-carboxamide
   Show/Hide
C21H17Cl2N3O
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466151
 Compound Info 
N-(4-methoxyphenyl)-7-pyridin-4-yl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide
   Show/Hide
C22H21N3O3
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Line ID: CL000006 , HEK293
 Cell Line Info