| Compound ID |
Compound Name |
Compound Formula |
|
CP0551183
|
(4S)-3'-(3,6-dihydro-2H-pyran-5-yl)-1'-fluoro-7'-(2-fluoropyridin-3-yl)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-c]pyridine]-2-amine
Show/Hide
|
C24H18F2N4O3
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0935597
|
N-((2R,3S)-3-{[(7-Ethyl-1-methyl-2,2-dioxido-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indol-9-yl)carbonyl]amino}-2-hydroxy-4-phenylbutyl)-2,6-dimethyl-2-heptanaminium formate
Show/Hide
|
C34H50N4O6S
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0943195
|
N-((2R,3S)-3-{[(7-Ethyl-1-methyl-2,2-dioxido-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indol-9-yl)carbonyl]amino}-2-hydroxy-4-phenylbutyl)cyclohexanaminium formate
Show/Hide
|
C31H42N4O6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0262731
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-3-hydroxy-4-[(6-methoxy-2,3-dihydro-1H-inden-1-yl)amino]-1-phenylbutan-2-yl]benzamide
Show/Hide
|
C33H42N4O5S
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0876278
|
(2R,3S)-3-{[(7-Ethyl-1-methyl-2,2-dioxido-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indol-9-yl)carbonyl]amino}-2-hydroxy-4-phenyl-N-{[3-(trifluoromethyl)phenyl]methyl}-1-butanaminium formate
Show/Hide
|
C33H37F3N4O6S
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0511437
|
3-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]-5-(2-methyl-5-oxocyclopent-1-en-1-yl)benzamide
Show/Hide
|
C33H35F3N2O4
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0489362
|
3-(2-cyanophenyl)-5-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C34H32F3N3O3
|
1
|
| 1 |
IC50 = 2020 nM
|
|
|
|
CP0876281
|
N-[(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-(ethylamino)phenyl]carbonyl}amino)-2-hydroxy-4-phenylbutyl]-2,6-dimethyl-2-heptanaminium formate
Show/Hide
|
C34H54N4O6S
|
1
|
| 1 |
IC50 = 2340 nM
|
|
|
|
CP0464299
|
N-[(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-{[(3-methoxyphenyl)methyl]amino}butan-2-yl]-3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide
Show/Hide
|
C31H38F2N4O5S
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0457705
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethoxy)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C31H37F3N4O5S
|
1
|
| 1 |
IC50 = 2570 nM
|
|
|
|
CP0170144
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-2-fluoro-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C31H36F4N4O4S
|
1
|
| 1 |
IC50 = 2653 nM
|
|
|
|
CP0464298
|
3-(2-acetylphenyl)-5-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C35H35F3N2O4
|
1
|
| 1 |
IC50 = 2940 nM
|
|
|
|
CP0486753
|
N-[(2S,3R)-4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3-hydroxy-1-phenylbutan-2-yl]-3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide
Show/Hide
|
C32H40N4O4S
|
1
|
| 1 |
IC50 = 3090 nM
|
|
|
|
CP0230205
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C31H37F3N4O4S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0935596
|
(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-(ethylamino)phenyl]carbonyl}amino)-2-hydroxy-4-phenyl-N-{[3-(trifluoromethyl)phenyl]methyl}-1-butanaminium formate
Show/Hide
|
C32H39F3N4O6S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0454076
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]-5-propylbenzamide
Show/Hide
|
C32H38F3N3O4S
|
1
|
| 1 |
IC50 = 4790 nM
|
|
|
|
CP0876279
|
N-[(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-ethylamino)phenyl]carbonyl}amino)-2-hydroxy-4-phenylbutyl]cyclohexanaminiumformate
Show/Hide
|
C30H44N4O6S
|
1
|
| 1 |
IC50 = 5250 nM
|
|
|
|
CP0454070
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C31H36F3N3O5S
|
1
|
| 1 |
IC50 = 5890 nM
|
|
|
|
CP0457720
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethoxy)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C31H36F3N3O6S
|
1
|
| 1 |
IC50 = 6170 nM
|
|
|
|
CP0455072
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-2-fluoro-N-[(2S,3R)-3-hydroxy-4-{[(3-methoxyphenyl)methyl]amino}-1-phenylbutan-2-yl]benzamide
Show/Hide
|
C31H39FN4O5S
|
1
|
| 1 |
IC50 = 6545 nM
|
|
|
|
CP0454075
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-3-hydroxy-4-{[(3-methoxyphenyl)methyl]amino}-1-phenylbutan-2-yl]benzamide
Show/Hide
|
C31H40N4O5S
|
1
|
| 1 |
IC50 = 6760 nM
|
|
|
|
CP0040694
|
BMCL193669 Compound 18
Show/Hide
|
C27H34N4O4S
|
1
|
| 1 |
IC50 = 7933 nM
|
|
|
|
CP0455080
|
3-(1,1-dioxo-1,2-thiazolidin-2-yl)-5-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]benzamide
Show/Hide
|
C30H34F3N3O5S
|
1
|
| 1 |
IC50 = 8510 nM
|
|
|
|
CP0418135
|
US9085576, 234
Show/Hide
|
C19H17F4N5O2
|
1
|
| 1 |
IC50 > 14800 nM
|
|
|
|
CP0575620
|
US9085576, 350
Show/Hide
|
C21H14ClF3N6O
|
1
|
| 1 |
IC50 > 14800 nM
|
|
|
|
CP0312779
|
US9296734, 18
Show/Hide
|
C20H14F8N6O
|
1
|
| 1 |
IC50 > 14800 nM
|
|
|
|
CP0518494
|
US9296734, 122
Show/Hide
|
C19H22F6N4O2
|
1
|
| 1 |
IC50 > 14800 nM
|
|
|
|
CP0454079
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-1-(furan-2-yl)-3-hydroxy-4-{[(3-methoxyphenyl)methyl]amino}butan-2-yl]benzamide
Show/Hide
|
C29H38N4O6S
|
1
|
| 1 |
IC50 = 15140 nM
|
|
|
|
CP0897223
|
N-[(2S,3R)-4-(benzylamino)-3-hydroxy-1-phenylbutan-2-yl]-3-ethyl-9-methyl-10,10-dioxo-10lambda6-thia-1,9-diazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraene-6-carboxamide;formic acid
Show/Hide
|
C32H38N4O6S
|
1
|
| 1 |
IC50 = 17180 nM
|
|
|
|
CP0220256
|
US9085576, 369
Show/Hide
|
C21H18F3N3O
|
1
|
| 1 |
IC50 = 19200 nM
|
|
|
|
CP0489349
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]-5-(propan-2-ylamino)benzamide
Show/Hide
|
C32H39F3N4O4S
|
1
|
| 1 |
IC50 = 25120 nM
|
|
|
|
CP0454078
|
BMCL181022 Compound 12
Show/Hide
|
C30H38N4O4S
|
1
|
| 1 |
IC50 = 26300 nM
|
|
|
|
CP0897224
|
(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-(ethylamino)phenyl]carbonyl}amino)-2-hydroxy-4-phenyl-N-(phenylmethyl)-1-butanaminium formate
Show/Hide
|
C31H40N4O6S
|
1
|
| 1 |
IC50 = 26300 nM
|
|
|
|
CP0894683
|
N-[(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-(ethylamino)phenyl]carbonyl}amino)-2-hydroxy-4-phenylbutyl]cyclopropanaminiumformate
Show/Hide
|
C27H38N4O6S
|
1
|
| 1 |
IC50 = 30200 nM
|
|
|
|
CP0501733
|
3-ethoxy-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trifluoromethyl)phenyl]methyl}amino)butan-2-yl]-5-(2-oxopyrrolidin-1-yl)benzamide
Show/Hide
|
C31H34F3N3O4
|
1
|
| 1 |
IC50 = 34325 nM
|
|
|
|
CP0227472
|
US9085576, 317
Show/Hide
|
C20H16ClF2N5O3
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
|
CP0334908
|
US9296734, 10
Show/Hide
|
C21H14F6N6O
|
1
|
| 1 |
IC50 > 44000 nM
|
|
|
|
CP0325626
|
US9085576, 363
Show/Hide
|
C21H15ClF2N6O
|
1
|
| 1 |
IC50 > 44400 nM
|
|
|
|
CP0342488
|
US9085576, 365
Show/Hide
|
C20H14F6N6O
|
1
|
| 1 |
IC50 > 44400 nM
|
|
|
|
CP0351266
|
US9085576, 343
Show/Hide
|
C21H15F3N6O
|
1
|
| 1 |
IC50 > 44400 nM
|
|
|
|
CP0491646
|
US9296734, 105
Show/Hide
|
C19H13ClF5N3O2
|
1
|
| 1 |
IC50 > 44400 nM
|
|
|
|
CP0234609
|
N-[3-[(1S,5S,6S)-3-amino-1-(difluoromethyl)-5-methyl-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4,5-difluorophenyl]-5-prop-2-ynoxypyrazine-2-carboxamide
Show/Hide
|
C21H17F4N5O2S
|
1
|
| 1 |
IC50 = 48000 nM
|
|
|
|
CP0575611
|
US9085576, 240
Show/Hide
|
C15H16F3N3O3
|
1
|
| 1 |
IC50 = 48150 nM
|
|
|
|
CP0274641
|
US9085576, 342
Show/Hide
|
C20H15ClF3N5O
|
1
|
| 1 |
IC50 = 50550 nM
|
|
|
|
CP0342492
|
US9085576, 221
Show/Hide
|
C20H16ClF2N5O3
|
1
|
| 1 |
IC50 = 51050 nM
|
|
|
|
CP0565147
|
US9085576, 376
Show/Hide
|
C17H17F6N3O
|
1
|
| 1 |
IC50 = 52900 nM
|
|
|
|
CP0519921
|
US9296734, 11
Show/Hide
|
C19H14ClF5N6O
|
1
|
| 1 |
IC50 = 54400 nM
|
|
|
|
CP0138372
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(2S,3R)-4-{[(1-ethyl-1H-pyrazol-4-yl)methyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-5-(ethylamino)benzamide
Show/Hide
|
C29H40N6O4S
|
1
|
| 1 |
IC50 = 56230 nM
|
|
|
|
CP0488860
|
US9085576, 338
Show/Hide
|
C21H20FN5O2
|
1
|
| 1 |
IC50 = 56550 nM
|
|
|
|
CP0117164
|
US9085576, 168
Show/Hide
|
C17H14F4N4O3
|
1
|
| 1 |
IC50 = 56750 nM
|
|
|
|
CP0876280
|
(2R,3S)-3-{[(7-Ethyl-1-methyl-2,2-dioxido-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indol-9-yl)carbonyl]amino}-2-hydroxy-N-methyl-4-phenyl-1-butanaminium formate
Show/Hide
|
C26H34N4O6S
|
1
|
| 1 |
IC50 = 58880 nM
|
|
|
|
CP0351270
|
US9085576, 370
Show/Hide
|
C22H21ClF3N3O
|
1
|
| 1 |
IC50 = 63600 nM
|
|
|
|
CP0522613
|
US9085576, 422
Show/Hide
|
C19H15ClF6N4O
|
1
|
| 1 |
IC50 = 68200 nM
|
|
|
|
CP0243743
|
US9085576, 378
Show/Hide
|
C19H18ClF3N4O
|
1
|
| 1 |
IC50 = 77400 nM
|
|
|
|
CP0239240
|
US9085576, 250
Show/Hide
|
C24H21F3N4O3
|
1
|
| 1 |
IC50 = 77500 nM
|
|
|
|
CP0117157
|
US9085576, 375
Show/Hide
|
C18H20F3N3O
|
1
|
| 1 |
IC50 = 78850 nM
|
|
|
|
CP0333537
|
US9085576, 449
Show/Hide
|
C20H14F6N6O
|
1
|
| 1 |
IC50 = 79350 nM
|
|
|
|
CP0266541
|
US9085576, 116
Show/Hide
|
C18H13BrF4N4O2
|
1
|
| 1 |
IC50 = 81884 nM
|
|
|
|
CP0243684
|
US9085576, 384
Show/Hide
|
C21H19BrF3N3O
|
1
|
| 1 |
IC50 = 82550 nM
|
|
|
|
CP0117156
|
US9085576, 372
Show/Hide
|
C22H22F3N3O
|
1
|
| 1 |
IC50 = 85450 nM
|
|
|
|
CP0243695
|
US9085576, 140
Show/Hide
|
C21H17ClF2N4O3
|
1
|
| 1 |
IC50 = 86900 nM
|
|
|
|
CP0455071
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(2S,3R)-4-{[(1-ethyl-1H-pyrazol-4-yl)methyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-5-(ethylamino)-2-fluorobenzamide
Show/Hide
|
C29H39FN6O4S
|
1
|
| 1 |
IC50 = 87100 nM
|
|
|
|
CP0477231
|
US9085576, 63
Show/Hide
|
C19H18F3N5O3
|
1
|
| 1 |
IC50 = 99750 nM
|
|
|
|
CP0464295
|
3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-[(2S,3R)-3-hydroxy-4-{[(3-methoxyphenyl)methyl]amino}-1-(1H-pyrazol-1-yl)butan-2-yl]benzamide
Show/Hide
|
C28H38N6O5S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0890931
|
3-(1,1-dioxo-1lambda*6*-[1,2]thiazinan-2-yl)-5-ethylamino-N-[(1S,2R)-2-hydroxy-1-isopropyl-3-(3-methoxy-benzylamino)-propyl]-benzamide
Show/Hide
|
C27H40N4O5S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0880740
|
(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-(ethylamino)phenyl]carbonyl}amino)-2-hydroxy-N-methyl-4-phenyl-1-butanaminium chloride
Show/Hide
|
C24H35ClN4O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0024522
|
N-[(2S)-1-[(3-fluoro-2-oxopropyl)amino]-1-oxo-3-phenylpropan-2-yl]benzamide
Show/Hide
|
C19H19FN2O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0030570
|
benzyl N-[(2S)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C21H23FN2O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0034074
|
N-[(2S)-1-[(3-fluoro-2-oxopropyl)amino]-1-oxo-3-phenylpropan-2-yl]naphthalene-1-carboxamide
Show/Hide
|
C23H21FN2O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0142132
|
US9085576, 180
Show/Hide
|
C19H16F4N4O3
|
1
|
| 1 |
IC50 > 1650 nM
|
|
|
|
CP0062694
|
US9296734, 177
Show/Hide
|
C21H14F6N6O
|
1
|
| 1 |
IC50 > 4940 nM
|
|
|
