General Information of the Protein
Protein ID
PT00646
Protein Name
Transient receptor potential cation channel, subfamily V, member 3
Gene Name
TRPV3
Sequence
MNAHSKEMVPLMGKRTTAPGGNPAVLTEKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKCIFAAVSEGCVRELRELLQDLQELCRRRRGLDASDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILGREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEIIVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPREDEALPHPLALTHKMSWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADSNKIQDSSRSNSKTTLYAFDELDEFPETSV
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Organism
Rattus norvegicus, Rat
Protein Classification
Unclassified protein
Uniprot ID
E9PU00
Subcellular Location
Membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0396602
 Compound Info 
(8aR,10aS)-8,8,10a-trimethyl-3-pentyl-6,7,8a,9-tetrahydro-5H-xanthen-1-ol
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C21H32O2
  2
1
EC50 = 6700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0390993
 Compound Info 
(2R,3'S)-1',1',3'-trimethyl-6-pentylspiro[3H-1-benzofuran-2,2'-cyclohexane]-4-ol
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C21H32O2
  1
1
IC50 = 12800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0390986
 Compound Info 
(2R,3'R)-1',1',3'-trimethyl-6-pentylspiro[3H-1-benzofuran-2,2'-cyclohexane]-4-ol
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C21H32O2
  1
1
IC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0390989
 Compound Info 
(7R,8aR,10aR)-7-iodo-8,8,10a-trimethyl-3-pentyl-6,7,8a,9-tetrahydro-5H-xanthen-1-ol
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C21H31IO2
  1
1
IC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0390991
 Compound Info 
2-methyl-2-[4-methyl-4-(4-methylphenyl)pentyl]-7-pentyl-3,4-dihydrochromen-5-ol
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C28H40O2
  1
1
IC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0396601
 Compound Info 
(8aR,10aR)-8,8,10a-trimethyl-3-pentyl-6,7,8a,9-tetrahydro-5H-xanthen-1-ol
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C21H32O2
  1
1
IC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
90% Identity
Protein ID Protein Name Protein Organism
PT00633 Heat sensitive channel TRPV3 Rattus norvegicus, Rat
 Protein Info 
PT06923 Transient receptor potential cation channel subfamily V member 3 Mus musculus, Mouse
 Protein Info