General Information of the Protein
Protein ID
PT00618
Protein Name
Ecdysone receptor
Secondarily
Protein Name
20-hydroxy-ecdysone receptor
EcRH
Ecdysteroid receptor
Nuclear receptor subfamily 1 group H member 1
Gene Name
ECR
Sequence
MDLKHEVAYRGVLPGQVKAEPGVHNGQVNGHVRDWMAGGAGANSPSPGAVAQPQPNNGYSSPLSSGSYGPYSPNGKIGREELSPASSINGCSTDGEARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVVPETQCAMKRKEKKAQKEKDKLPVSTTTVDDHMPPIMQCEPPPPEAARIHEVVPRFLSDKLLETNRQKNIPQLTANQQFLIARLIWYQDGYEQPSDEDLKRITQTWQQADDENEESDTPFRQITEMTILTVQLIVEFAKGLPGFAKISQPDQITLLKACSSEVMMLRVARRYDAASDSVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYSMALDNIHYALLTAVVIFSDRPGLEQPQLVEEIQRYYLNTLRIYILNQLSGSARSSVIYGKILSILSELRTLGMQNSNMCISLKLKNRKLPPFLEEIWDVADMSHTQPPPILESPTNL
    Show/Hide
Organism
Choristoneura fumiferana, Spruce budworm moth, Archips fumiferana
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 1
Uniprot ID
O77240
Subcellular Location
Nucleus
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
Compound ID Compound Name Compound Formula
CP0001249
3-methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
   Show/Hide
C22H28N2O3
 1
1
EC50 = 280 nM
   TI
   LI
   LO
   TS
CP0437094
5-Ethyl-2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid [1-(3,5-dimethyl-benzoyl)-cyclohexyl]-amide
   Show/Hide
C26H31NO4
 1
1
EC50 = 390 nM
   TI
   LI
   LO
   TS
CP0430118
3,5-Dimethyl-benzoic acid N-tert-butyl-N'-(2-ethyl-3-methoxy-benzoyl)-hydrazide
   Show/Hide
C23H30N2O3
 1
1
EC50 = 410 nM
   TI
   LI
   LO
   TS
CP0448845
3-Methoxy-N-[1-(2-methoxy-benzoyl)-cyclohexyl]-2-methyl-benzamide
   Show/Hide
C23H27NO4
 1
1
EC50 = 1030 nM
   TI
   LI
   LO
   TS
CP0383048
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-3-methoxy-2-methylbenzamide
   Show/Hide
C24H29NO3
 1
1
EC50 = 1110 nM
   TI
   LI
   LO
   TS
CP0402202
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-2-ethyl-3-methoxybenzamide
   Show/Hide
C25H31NO3
 1
1
EC50 = 1250 nM
   TI
   LI
   LO
   TS
CP0430327
N-[4-(3,5-dimethylbenzoyl)thian-4-yl]-3-methoxy-2-methylbenzamide
   Show/Hide
C23H27NO3S
 1
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0463474
N-[1-(3,5-dimethylbenzoyl)cyclopentyl]-3-methoxy-2-methylbenzamide
   Show/Hide
C23H27NO3
 1
1
EC50 = 1910 nM
   TI
   LI
   LO
   TS
CP0429891
N-[1-(3,5-dimethylbenzoyl)cycloheptyl]-3-methoxy-2-methylbenzamide
   Show/Hide
C25H31NO3
 1
1
EC50 = 2970 nM
   TI
   LI
   LO
   TS
CP0463389
4-Methyl-benzo[1,3]dioxole-5-carboxylic acid [1-(3,5-dimethyl-benzoyl)-cyclohexyl]-amide
   Show/Hide
C24H27NO4
 1
1
EC50 = 3220 nM
   TI
   LI
   LO
   TS
CP0422301
3-Methoxy-N-[1-(2-methoxy-benzoyl)-cycloheptyl]-2-methyl-benzamide
   Show/Hide
C24H29NO4
 1
1
EC50 = 3360 nM
   TI
   LI
   LO
   TS
CP0391452
N-[3-(3,5-dimethylbenzoyl)pentan-3-yl]-3-methoxy-2-methylbenzamide
   Show/Hide
C23H29NO3
 1
1
EC50 = 6230 nM
   TI
   LI
   LO
   TS
CP0464946
3-Methoxy-N-[1-(2-methoxy-benzoyl)-cyclopentyl]-2-methyl-benzamide
   Show/Hide
C22H25NO4
 1
1
EC50 = 6610 nM
   TI
   LI
   LO
   TS
CP0384012
N-[4-(3,5-dimethylbenzoyl)oxan-4-yl]-3-methoxy-2-methylbenzamide
   Show/Hide
C23H27NO4
 1
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0460877
N-[1-(3,5-dimethylbenzoyl)cyclobutyl]-3-methoxy-2-methylbenzamide
   Show/Hide
C22H25NO3
 1
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0382994
N-[4-(3,5-dimethylbenzoyl)-1,1-dioxothian-4-yl]-3-methoxy-2-methylbenzamide
   Show/Hide
C23H27NO5S
 1
1
EC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0374700
N-[1-(3,5-dimethylbenzoyl)cyclopropyl]-3-methoxy-2-methylbenzamide
   Show/Hide
C21H23NO3
 1
1
EC50 = 33300 nM
   TI
   LI
   LO
   TS
CP0506397
N-[1-(3,5-dimethylphenyl)-2-methyl-1-oxopropan-2-yl]-3-methoxy-2-methylbenzamide
   Show/Hide
C21H25NO3
 1
1
EC50 = 41950 nM
   TI
   LI
   LO
   TS